Interventional Oncology

Drug Elutable Microspheres

Terumo Interventional Oncology Division presents LifePearl, a precise answer to a challenge in interventional oncology. LifePearl are PEG (polyethylene glycol) embolization microspheres that can be loaded with chemotherapeutic agents (such as Doxorubicin, Irinotecan, Idarubicin and Epirubicin).

LifePearl offers:

• Wide range of drug loading options1
• Enhanced suspension characteristics2, 4, 5
• Tight calibration3, 4, 5
• Syringe presentation

Veloso et al reported results from one of the largest multicentric cohorts of unresecable HCC patients (n=580) treated with LifePearl™ microspheres to date6:

• Over 4 years Median OS (50.8 months [95% CI 44.7–NE])
• 60.1% complete response rate exceeding what is reported in previous studies 7,8,9

Characteristics

​LifePearlTM microspheres are designed to actively absorb drugs into their matrix2

• 37.5 mg of Doxorubicin per 1 ml of LifePearl® microspheres
• 5mg of Idarubicin per 1ml of LifePearl® microspheres
• 25mg of Epirubicin per 1ml of LifePearl® microspheres
• 50.0 mg of Irinotecan per 1 ml of LifePearl® microspheres

Temporary Occlusion Balloon Catheter
 

• Through Pressure Gradient Effect, Occlusafe™ as micro-balloon catheter, offers the ability to redistribute blood flow and access the microcirculation, leading to an increased accumulation of therapeutics into the target lesion with minimal off-target embolization.
• This may be associated with improved clinical outcomes in challenging lesions.

Overview

A technical revolution in transarterial embolization

• Through Pressure Gradient Effect, Occlusafe™ as micro-balloon catheter, offers the ability to redistribute blood flow and access the microcirculation, leading to an increased accumulation of therapeutics into the target lesion with minimal off-target embolization.
• This may be associated with improved clinical outcomes in challenging lesions.

Diagnostic Catheter

Hydrophilic Coated Catheter
Developed to be the dedicated shape/length for Radial Access for Visceral Intervention (R.A.V.I.).

Overview

• A hydrophilically coated, angiographic catheter providing vessel selectivity and navigation
• Developed to be the dedicated shape/length for Radial Access for Visceral Intervention (R.A.V.I.).
• Navigate difficult vessel anatomy with smooth tracking facilitated by TERUMO Glide Technology™
• Leverage superior kink resistance to achieve ideal flow rates for diagnostic imaging1,*

Superior Trackability

• Traverse tortuous anatomy while leveraging a superior ability to deliver devices through a nylon rich inner layer

Superior Torqueability

• Engage acute vessels with superior torque control with a double-braided design

Excellent Lubricity

• Navigate difficult vasculature with the excellent lubricity provided by Terumo Glide Technology

Diagnostic Catheter

Hydrophilic Coated Catheter
Navigate difficult vessel anatomy with smooth tracking facilitated by Mcoat™.
Better kink resistance to achieve ideal flow rates for diagnostic imaging.

Overview
• A hydrophilically coated, angiographic catheter providing the vessel selectivity and navigation required for a wide variety of diagnostic or interventional procedures
• Navigate difficult vessel anatomy with smooth tracking facilitated by Mcoat™.
Better kink resistance to achieve ideal flow rates for diagnostic imaging

Product Details
Single-Braided (5F)
• Reach distal visceral vessels with best-in-class trackability and torquability.

Double-Braided (4F)
• Access and cross challenging lesions with excellent trackability and torquability.

Guidewire

Radifocus Guidewire GT is Terumo’s solution for access and navigation in peripheral and cerebral procedures.
• It is indicated for use in distal catheterization, selective, and superselective embolization in small, distal, angular, and sensitive peripheral and neurological vasculature.
• 25 cm distal taper designed to minimize vessel trauma that may improve selectivity of vessels
• Choose from a wide selection of tip angles, including the unique double angle, to help navigate and select even the most acutely angled vessels

TERUMO Glide Technology™ hydrophilic coating
• Provides unmatched lubricity
• Provides superior lubricity retention

TERUMO nitinol alloy core
• Resists kinking for easier, faster navigation through even the most tortuous vessels
• Restores shape to manufactured state for multiple uses in a single procedure

2 cm gold coil at distal tip
• Provides enhanced radiopacity of tip for optimal visibility

Polyurethane jacket with tungsten
• Provides enhanced radiopacity of entire GLIDEWIRE® GT Guidewire

Core-to-tip design
• Designed to provide optimal torque control and navigation

Micro Catheter System

This catheter is for angiography and intravascular therapy. The catheter has a hydrophilic polymer coating on the surface over its entire length except its proximal end. The coating gives it lubricity when it is wet. When infusing a contrast media through the catheter, a power injector can be used.

Overview

Master complexity with excellent branch selectivity

This catheter is for angiography and intravascular therapy. The catheter has a hydrophilic polymer coating on the surface over its entire length except its proximal end. The coating gives it lubricity when it is wet. When infusing a contrast media through the catheter, a power injector can be used.